Reproductive Toxicity of Sulfur Dioxide Derivatives on Sperms of Mice

To investigate the reproductive toxicity effect of sulfur dioxide(SO_(2)) derivatives(the mixture of sodium sulfite and sodium bisulfite,c : c = 3 : 1),the damaging effect of SO_(2) derivatives on sperms of male Kunming mice was studied.Mice were continually injected through intraperitoneal route with SO_(2) derivatives once a day for 5 days.The mice were killed on d 35 after the first injection.Then the sperm activity,sperm quantity and sperm deformity of the mice were recorded and analyzed.The results showed:(1) SO_(2)derivatives caused a decrease in the sperm quantity and an increase in inactivity sperm quantity in a dose-dependent manner;(2) SO_(2)derivatives caused an increase in various types of sperm deformity,especially the increase in inconstant shapes of sperm deformity.In addition,SO_(2)derivatives led to an increase in percentage of sperms with deformity in a dose-dependent manner.These results suggested that SO_(2) pollution had reproductive toxicity effect on male creature,and more attention should be paid to the effect of SO_(2) pollution.Fig 1,Tab 2,Ref 14