The clinical application of biomarkers in pediatric sepsis

Sepsis is still a leading cause of death in infants and children.It is the result of multiple organ dysfunction syndrome caused by infection.For sepsis, early diagnosis is very important.Biomarkers (procalcitonin, C-reactive protein, pro-inflammatory cytokines, white blood cell count, neutrophil count, left shift and CD64) during the response to infection can be used for early diagnosis.In addition, continuously monitoring these biomarkers can be used for evaluating severity of illness, monitoring of treatment responses and predicting outcome. Key words: Sepsis; Children; Biomarkers,