Epigenetic regulation of HOTAIR in advanced chronic myeloid leukemia

Ziye Li,Jianmin Luo

Epigenetic regulation of HOTAIR in advanced chronic myeloid leukemia

2018

Ziye Li
Jianmin Luo

Purpose Chronic myeloid leukemia (CML) accounts for ~10% of leukemia cases, and its progression involves epigenetic gene regulation. This study investigated epigenetic regulation of HOTAIR and its target microRNA, miR-143, in advanced CML.

Keywords:

Myeloid leukemia
HOTAIR
Cancer research
Biology
Epigenetics
EZH2
Methyltransferase
K562 cells
Leukemia
microRNA
Regulation of gene expression
Chemistry

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