Patients׳ perspectives on how treatment can impede their recovery from depression.

Background: More than 50% of all major depressive disorder (MDD) patients experience insufficient improvement from the available treatment options. There is emerging evidence that patients' beliefs and experiences about MDD treatment influence treatment outcomes. The aim was to explore patients' perspectives on impeding characteristics of professional treatment for the recovery of MDD. Methods: In-depth interviews in a purposive sample with 27 recovered MDD patients who had received professional treatment. Data were qualitatively analyzed using constant comparison. Results: Participants' accounts yielded four major impeding themes: lack of clarity and consensus about the nature of the participants' MDD and the content of their treatment; precarious relationship with the clinician; unavailability of mental health care; and insufficient involvement of significant others. Limitations: The external generalizability may be limited due to missed other subgroups within depression. Conclusions: This study identified a comprehensive overview of impeding characteristics in MDD treatment from patients' perspectives. This may help clinicians to understand how patients experience MDD treatment, and to incorporate patients' perspectives about treatment into their joint decisionmaking. This can lead towards increased treatment adherence, motivation and finally success.