Patch based super-resolution of MR spectroscopic images

In this paper, a new single-image super-resolution method is presented to increase the spatial resolution of metabolite maps computed from magnetic resonance spectroscopic imaging. The proposed method is based on a non-local patch-based strategy that uses a high resolution T1-weighted image to regularise the super-resolution process. The method is implemented in a multi-scale fashion. The accuracy of the method is validated on both phantom and in vivo images. Both qualitative and quantitative validation suggest that the method has potential for clinically relevant neuroimaging applications.