Expression of CDX2, cytokeratins 7 and 20 in sinonasal intestinal-type adenocarcinoma.

Abstract:CDX2 is a transcription factor expressed by intestinal epithelium. It is considered as a sensitive marker for a colorectal or-less frequently-gastric origin of adenocarcinomas. The pattern of coordinated expression of cytokeratin (CK) 7 and CK20 is also useful for the diagnosis of the origi