MP80-12 SUSTAINED IMPROVEMENTS IN URINARY INCONTINENCE AND QUALITY OF LIFE OVER LONG-TERM TREATMENT WITH ONABOTULINUMTOXINA IN PATIENTS WITH URINARY INCONTINENCE DUE TO NEUROGENIC DETRUSOR OVERACTIVITY

(18.5%) void, 41 (63.1%) perform clean intermittent catheterization (CIC), 4 (6.2%) use an indwelling catheter, 3 (4.6%) have an ileal conduit (IC), and 5 (7.7%) mainly use diapers. Average SF-36 General Health score was 56.5 (SD 22.9) and average I-QOL Sum score was 50.9 (SD 21.7), where lower scores reflect lower QOL. The 8 SF-36 and 3 I-QOL domains were not significantly different with and without urologic reconstruction or based on ambulatory status. No I-QOL scales significantly differed based on bladder management technique; with SF-36 questionnaires, general health rating significantly differed (p1⁄40.027) with highest scores in patients managed with voiding, followed by CIC, IC and diapers, with lowest scores with indwelling catheters. A correlation was noted between I-QOL scales and most SF-36 scales (all p<0.02). CONCLUSIONS: Urologic reconstruction and bladder management techniques have evolved in SB patients and affect patients’ daily urinary regimens. In our cohort of adult SB patients, although bladder management technique and urologic reconstruction did not affect scores in the urinary (I-QOL) or general health (SF-36) domains, I-QOL scores correlated with SF-36 scores. Thus, urinaryrelated QOL is significantly related to overall QOL. However, we are unable to identify a single factor (ambulatory status, reconstruction, management technique, sex, age) that improved either urinary or overall QOL. We need to continue to study the effect of bladder management technique preand post-operatively, over time with urologic reconstruction on overall health and urinary QOL in the SB population.