Properties and applications of powdered polysaccharide acids. I. Preparation and titration curves

Several new powdered polysaccharide acids, namely elm acid, quince acid, and plantago acid, were prepared by ion exchange, followed by spray drying. These acids, carboxymethylcellulose acid and several analogous type acids were titrated potentiometrically, and the shape of the titration curves were indicated to be quite typical of the synthetic cation exchangers. Approximate acid equivalents and pKa values were determined for some of these substances. A number of pharmaceutical applications for these acids are suggested.