Chemical constituents of Menispermum dauricum

Abstract Aim To study the chemical constituents of Menispermum dauricum DC. Methods Compounds were isolated by repeated chromatography on silica gel and Sephadex LH-20. The structures were identified by spectral analysis and comparison with literature data. Results Eleven compounds were obtained and identified as dauricumine ( 1 ), dauricumidine ( 2 ), acutuminine ( 3 ), physcion ( 4 ), blumenol C ( 5 ), blumenolA ( 6 ), N-trans feruloyltyramine ( 7 ), vanillin ( 8 ), β-sitostenone ( 9 ), β-sitosterol ( 10 ), and daucosterol ( 11 ). Conclusion All compounds were known, but isolated from the plant for first time. Compounds 1 and 2 were chlorine-containing alkaloids obtained from natural source for the first time. The stereochemistry of 3 was determined for first time.