Disagreement between tissue Doppler imaging and conventional pulsed wave Doppler in the measurement of myocardial performance index

Aim: Myocardial performance index (MPI) is usually measured with pulsed wave Doppler (PWD). Our aim was to assess the degree of agreement be- tween PWD and a method based on tissue Doppler imaging (TDI). Methods and results: Seventy-five patients with prior myocardial infarction and 20 healthy subjects underwent measurement of time intervals and MPI with PWD and pulsed TDI at septal and lateral sides of mitral annulus. MPI and TDI-MPI at septal side showed the best intraclass correlation coefficient (ICC Z 0.54; p ! 0.0005). Ninety-five percent interval of agreement ranged from 0.27 to 0.22. These differ- ences were attributed to discrepancies in isovolumic contraction and relaxation times. In the healthy group the results were similar (ICC Z 0.44), although the 95% interval of agreement was lower (from 0.13 to 0.12). Conclusions: The agreement between PWD and TDI in the measurement of MPI is only moderate. This should be taken into account in the interpretation of studies