Differential induction of antibody-dependent cellular cytotoxicity (ADCC) against human EGFR-expressing NSCLC cell lines by necitumumab, cetuximab, and panitumumab.

Dipa Patel,B. Saxena,Qinwei Zhou,W. Walton,R. Srikakulum,R Manteiga,J. Haurum,J. R. Tonra,Xiaoqiang Kang

Differential induction of antibody-dependent cellular cytotoxicity (ADCC) against human EGFR-expressing NSCLC cell lines by necitumumab, cetuximab, and panitumumab.

2011

Dipa Patel
B. Saxena
Qinwei Zhou
W. Walton
R. Srikakulum
R Manteiga
J. Haurum
J. R. Tonra
Xiaoqiang Kang

e21075 Background: Necitumumab, cetuximab and panitumumab are monoclonal antibodies specific for human epidermal growth factor receptor (EGFR). They act as functional antagonists by blocking ligand...

Keywords:

Necitumumab
Cetuximab
Cancer research
Pathology
Antibody-dependent cell-mediated cytotoxicity
Panitumumab
Cell culture
Medicine
nsclc cell
human epidermal growth factor receptor
Monoclonal antibody

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