Effects of the most frequently used solutions and ointments in routine surgical practice

The authors tested the effect of local antiseptics commonly used at the Clinic of Plastic and Aesthetic Surgery in Brno on bacteria which most frequently infect extensive skin defects. The experiments were carried out in vitro and in vivo in a group of experimental animals. In vivo the effect on Staphylococcus aureus and Pseudomonas aeruginosa was investigated, in vitro also the effect on Proteus mirabilis. The authors found that 0.1% Persteril, Peru balsam, and Dermazine ung./Lek Co./exerted a very favourable effect on the tested microorganisms. A weaker effect was recorded after Vishnevsky balsam and 0.5% Rivanol. 0.5% gentian violet and 3% boricacid had no effect on P. aeruginosa, 0.05% permanganate and 2% Jodonal had no effect on staphylococci.