MP31-15 RENAL MASS BIOPSY VS. BIOPSY OF MASSES IN OTHER ORGANS: WHY IS IT DIFFERENT ONLY FOR THE KIDNEY?

INTRODUCTION AND OBJECTIVES:In urology, renal mass biopsy among patients with an image-detected small renal mass (i.e. ≤ 4 cm) is currently not the standard of care; instead, most urologists proceed with extirpative therapy despite the knowledge that 20% of these masses are benign. For all other solid, organ-confined masses (e.g. prostate, bladder, lung, breast, etc.), the standard of care mandates a biopsy-established diagnosis prior to treatment. In order to discern why the kidney is an outlier for pre-treatment biopsy, we sought to compare the efficacy and safety of renal mass biopsy to biopsy of a mass in other major solid organ systems.METHODS:We reviewed meta-analyses, systematic reviews, and clinical studies with regard to biopsy of a mass in the following organs: prostate, lung, breast, thyroid, pancreas, and kidney. Rigorous study designs that minimized bias and systematic error were identified; only reports dealing exclusively with needle biopsy were included.RESULTS:Organ-specific mass biopsy d...