Prevalência de síndrome metabólica e fatores associados em pacientes transplantados renais

Among the 87 pa- tients enrolled, 39 (44.8%) presented the phenotype of metabolic syndrome. The mean age of the patients was 43.5 ± 12.1 years-old, with a predominance of male (69.0%) and white (66.7%). The mean and median times of post transplant fol-low-up were 64.2 ± 49.4 and 56 months, respectively. All the 12 patients who de-veloped post-transplant diabetes mellitus also met the criteria for metabolic syn-drome, which compromised the inclusion of this variable in the logistic regression. In the univariate analysis, patients with metabolic syndrome had higher mean age (p = 0.008), higher median blood level of cyclosporine (p = 0.021), higher prevalence of history of coronary disease (p = 0.023), and they were more frequent users of beta (p = 0.011) and calcium- channel blockers (p = 0.039). In the multivariate analysis, age (HR = 1.06; 95% CI=1.01-1.11, p=0.006) and use of beta-block-ers (HR = 4.02; 95% CI = 1.41 - 11.4, p = 0.009) were asso- ciated with increased