Chemopreventive Role of Dietary Phytochemicals in Colorectal Cancer

Abstract Colorectal cancer is one of the leading causes of morbidity and mortality globally, which accounts for 0.7 million deaths in 2015. Despite the fact that tremendous advancement had been achieved in research and development in medicine, the colorectal cancer-related deaths are ascending continuously thus, the research community has come up with chemoprevention, a novel and innovative way to reduce colorectal cancer. Chemoprevention therapies use several pharmacological agents having negative influences on human health and to overcome this natural products are used now-a-days, as being reported. Various epidemiological studies have associated the consumption of some dietary phytochemicals with lower risk of colorectal cancer development. Here in this chapter, we summarize the chemopreventive effect of dietary phytochemicals, their availability, in vitro and in vivo effects on colorectal cancer, and clinical studies. This review describes the promising effect of dietary phytochemicals in colorectal cancer intervention.