Morphological and functional state of the thymus and lymphatic system during development of adaptive reactions to electrical stimulation of emotiogenic brain structures

Mental stress, and negative emotions forming physicoemotional stress, lead to disturbances of the immune status or even to the formation of immunodeficiency states [4]. A characteristic feature of stress is hypoplasia of lymphoid tissue of the thymus and lymph nodes. Besides stress, the general nonspecific adaptive response (GNAR) to any extremal or strong stimuli, the GNAR to various stimuli of physiological parameters, namely weak, or threshold strength -the training reaction [2, 3], and stimuli of average strength and the activation reaction [i], differing qualitatively from stress, have been described. During the training reaction moderate functional activity is observed in the thymus and lymphatic system (TLS), and the architectonics of the structures of TLS corresponds to the pattern given in textbooks of histology, whereas in the activation reactions, there is high functional activity, expressed mainly as hyperplasia of lymphoid tissue [5].