EXTRA AMNIOTIC PROSTAGLANDINS IN THE MANAGEMENT OF INTRAUTERINE FETAL DEATH, ANENCEPHALY AND HYDATIDIFORM MOLE

Summary Prostaglandin E2 or prostaglandin F2α was administered extra-amniotically in the treatment of 22 cases of intrauterine fetal death, two of anencephaly and one of hydatidiform mole. Delivery was achieved in 24 out of the 25 patients. The choice of the extra-amniotic route of administration appeared to result in fewer side effects than have been encountered during intravenous prostaglandin therapy in the treatment of these conditions.