Standardized uptake value in high uptake area on positron emission tomography with 18F-FRP170 as a hypoxic cell tracer correlates with intratumoral oxygen pressure in glioblastoma.

Takaaki Beppu,Kazunori Terasaki,Toshiaki Sasaki,Shunrou Fujiwara,Hideki Matsuura,Kuniaki Ogasawara,Koichiro Sera,Noriyuki Yamada,Noriyuki Uesugi,Tamotsu Sugai,Kohsuke Kudo,Makoto Sasaki,Shigeru Ehara,Ren Iwata,Yoshihiro Takai

Standardized uptake value in high uptake area on positron emission tomography with 18F-FRP170 as a hypoxic cell tracer correlates with intratumoral oxygen pressure in glioblastoma.

2014

Takaaki Beppu
Kazunori Terasaki
Toshiaki Sasaki
Shunrou Fujiwara
Hideki Matsuura
Kuniaki Ogasawara
Koichiro Sera
Noriyuki Yamada
Noriyuki Uesugi
Tamotsu Sugai
Kohsuke Kudo
Makoto Sasaki
Shigeru Ehara
Ren Iwata
Yoshihiro Takai

Purpose The aim of this study was to clarify the reliability of positron emission tomography (PET) using a new hypoxic cell tracer, 1-(2-[18F]fluoro-1-[hydroxymethyl]ethoxy)methyl-2-nitroimidazole (18F-FRP170).

Keywords:

Medicine
Nuclear medicine
Radiology
Glioblastoma
Standardized uptake value
Positron emission tomography
oxygen pressure
TRACER
high uptake
hypoxic cell
Hypoxia (medical)

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