Reply to Peiretti et al.: Effect of CAGE on fat uptake and food intake

We thank Peiretti et al. (1) for their interest in our work (2) and for the suggestions for follow-up research. Peiretti et al. (1) ask about the role of reduced food consumption in the observed effect on reduced weight gain. We respectfully acknowledge this question. In our work (2), the effect of choline and geranate (CAGE) on fat uptake is hypothesized to occur primarily through a physical phenomenon. Specifically, the amphiphilic nature of CAGE enables its interactions with the lipophilic fat molecules … [↵][1]1To whom correspondence may be addressed. Email: mitragotri{at}seas.harvard.edu. [1]: #xref-corresp-1-1