Solid phase synthesis of retro-inverso peptide analogues. Synthesis of a partially modified retro-inverso analogue of substance P, [Glp6, gPhe8, mGly9] SP6–11[gPhe =–NHCH(CH2Ph)NH–,mGly =–OCCH2CO–]

The complete solid phase synthesis of a partially modified retro-inverso analogue of Substance P, [Glp6, gPhe8, mGly9]SP 6–11, [gPhe =–NHCH(CH2Ph)NH–, mGly =–OCCH2CO–] has been performed using a polydimethylacrylamide-based solid support and [bis(trifluoroacetoxy)iodo]benzene.