Monomeric and dimeric beta 2-microglobulin may be extracted from amyloid deposits in vitro.

studies on b 2 M amyloidosis show that once the amyloid Conclusions. These results show that the protein con- deposits are formed, there is no degradation in vivo, stituents may be recovered from amyloid fibrils in vitro. even after the primary cause of amyloidosis disappears They also show that even the more insoluble b 2 M [15‐19 ]. We have recently reported the persistence of amyloid deposits as well as an accelerated course of