Determinação fenotípica das haptoglobinas em pacientes com dor crônica causada por desordens temporomandibulares
2010
The phenotypes of the hemoglobin-haptoglobin (Hb-
Hp) system were measured in 124 subjects, 100 patients
with chronic pain in temporomandibular disorders and
24 normal, without any bodily pain during the years
2000 -2003. The system Hb-Hp showed polymorphism
Hp1-1, Hp2-1 and Hp2-2, at 100% and 85% respectively;
anahaptoglobinemia (Hp0) in 15% of the sample
studied. Hp1-1 genotype was present significantly
(p < 0, 0001) in patients with TMDs, regardless the clinical
type TMD, suggesting that Hp1-1 and likely genetic
marker of susceptibility for the development of chronic
pain in TMD.
Key words: Temporomandibular joint. Pain. Haptoglobin.
Polymorphism genetic.
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