Analysis on human papillomavirus 16 and 18 types infection among 805 patients with common anorectal lesions

Objective To analyze the infection condition of human papillomavirus (HPV) type 16 and 18 in the squamous cells and columnar ceils of patients with common anorecatal lesions.Methods Infections of HPV type 16 and 18 were determined with real-time fluorescent quantitative PCR in the wax-embedded surgical specimen of 805 patients with common anorectal diseases.Results The overall infection rate among 805 patients with anorecatal lesions was 66.1％(532/805).The infection rate was 82.6％(95/115) in patients with mixed hemorrhoids,76.5％(88/115) in anal papillary fibromas,74.8％(86/115) in internal hemorrhoids,72.2％(83/115) in fistulas,69.6％(80/115) in external hemorrhoids,47.8％(55/115) in anal perianal abscesses,and 39.1％(45/115) in anal fissures.Conclusion Infection rate of HPV type 16,18 in common anorectal lesions is high. Key words: Human papillomavirus;  Anorectum lesion;  Polymerase chain reaction