Vasohibin 2 reduces chemosensitivity to gemcitabine in pancreatic cancer cells via Jun proto-oncogene dependent transactivation of ribonucleotide reductase regulatory subunit M2.

Min Tu,Haifeng Li,Nan Lv,Chunhua Xi,Zipeng Lu,Jishu Wei,Jianmin Chen,Feng Guo,Kuirong Jiang,Guoxin Song,Wentao Gao,Yi Miao

Vasohibin 2 reduces chemosensitivity to gemcitabine in pancreatic cancer cells via Jun proto-oncogene dependent transactivation of ribonucleotide reductase regulatory subunit M2.

2017

Min Tu
Haifeng Li
Nan Lv
Chunhua Xi
Zipeng Lu
Jishu Wei
Jianmin Chen
Feng Guo
Kuirong Jiang
Guoxin Song
Wentao Gao
Yi Miao

Background Vasohibin 2 (VASH2) has previously been identified as an agiogenenic factor and a cancer related protein. Here we investigated the association of VASH2 expression and chemoresistance in pancreatic cancer.

Keywords:

Molecular biology
Transactivation
Cancer
Cancer research
Biology
Pancreatic cancer
Vasohibin 2
Gemcitabine
Ribonucleotide reductase regulatory subunit M2
Oncogene

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