Brote de enfermedad de Grover durante la pandemia de Covid-19.

Introduccion: La enfermedad de Grover (EG) es una dermatosis acantolitica caracterizada por papulas eritematosas, vesiculas y costras localizadas principalmente en tronco, pruriginosas, de curso persistente, recurrente o cronico. Afecta a hombres de mediana edad, de ascendencia caucasica y europea. Existen factores desencadenantes como exposicion a la luz solar, calor, sudoracion, aire frio y seco, e inmunosupresion. Durante la pandemia de COVID-19, en una practica privada de dermatopatologia se reportaron 6 biopsias de pacientes con EG en 3 meses; previamente se reportaban 3 a 5 pacientes anuales desde el ano 2003. El objetivo del estudio es reportar un aumento de los casos de EG entre junio y agosto del 2020 y tratar de dilucidar los factores desencadenantes de este brote. Materiales y Metodos: estudio observacional, descriptivo y transversal de una serie de casos de pacientes con biopsias diagnosticadas como EG recibidas entre junio y agosto del 2020 en una practica privada de dermatopatologia. Se obtuvieron los datos mediante las solicitudes de biopsias y comunicacion telefonica con el dermatologo tratante. Resultados: se reportaron 6 casos con diagnostico histopatologico de EG. Predomino el sexo masculino, todos mayores de 50 anos. En los meses de abril y mayo se registro un aumento de la temperatura media en Caracas, con una maxima de 25,8°C y una humedad relativa mas baja del 61%. Discusion: este brote de casos de EG puede atribuirse a stress y cambios de habitos de vida inducidos por el confinamiento asociado a la pandemia de COVID-19, aumento de la temperatura media y disminucion de la humedad en los meses previos al brote. Grover´s disease outbreak during covid-19 pandemic. Summary Introduction: Grover's disease (GD) is an acantholytic dermatosis characterized by pruritic erythematous papules, vesicles and crusts distributed mainly in the trunk. The curse is transient, persistent or chronic. It affects middle-aged men of Caucasian and European descent. There are triggers such as sunlight exposure, heat, sweating, cold and dry air, and immunosuppression. During the COVID-19 pandemic, a private dermatopathology practice reported 6 biopsies of EG patients in 3 months; previously, 3 to 5 patients were reported annually since 2003 in this practice. The objective of the study is to report an increase in GD cases between June and August 2020 and to try to elucidate the triggers for this outbreak. Materials and Methods: observational, descriptive and cross sectional study of series of cases of patients with biopsies diagnosed as GD received between June and August 2020 in a private dermatopathology practice. The data was obtained through biopsy requests forms and telephone communication with the treating dermatologist. Results: 6 cases with histopathological diagnosis of EG were reported. Male gender was predominant and all the patients were over 50 years old. In April and May 2020, there was an increase in the average temperature in Caracas, with a maximum of 25.8°C and a lower relative humidity of 61%. Discussion: This outbreak of GD cases can be attributed to stress and lifestyle changes induced by confinement associated with the COVID-19 pandemic, increased average temperature and decreased humidity in the months previous to the outbreak. Key words: outbreak; Grover´s disease; acantholytic dermatosis, COVID-19.