High-Risk Human Papillomavirus Screening of Gynecologic Specimens: Comparison of the Roche cobas 4800 With the Hologic Cervista Assays

With the commercial availability of new high-risk HPV screening assays, we sought to compare a real-time PCR-based assay with our current signal amplification assay. The Cobas 4800 HPV assay (Roche Molecular Diagnostics, Indianapolis, IN) recently received FDA approval for detection of 14 HR-HPV genotypes: HPV-16 and HPV-18 are each identified separately and the other 12 HR-HPV genotypes are identified …