Sutureless colic anastomoses with cyanocrylates
2011
BACKGROUND AND AIMS. The present research project has been made mainly with the idea of comparing the tensile strength
values and histological answers of three types of colon anatomises: sutured with silk and sutureless anastomoses with 2-octylcyanocrylate
and N-butyl-2-cyanoacrylate.
METHODS. 112 Wistar rats distributed into three groups of 35 animals and a last control group of 7 have been used for this.
Group 1: silk, group 2: 2-octyl-cyanocrylate, group 3: N-butyl-2-cyanoacrylate, group 4: Control group. The following surgical
interventions were practiced on them: A cross section of the colon, followed by: group 1: an end-to-end discontinuous
suture anastomoses with Silk; group 2: sutureless anastomoses with 2-octyl-cyanocrylate; group 3: sutureless anastomoses
with N-butyl-2-cyanoacrylate. On the 10th, 20th, 30th, 40th and 50th days we proceeded to measure the anastomoses' tensile
strength value for each series. In the same period of time we carried out the following anatomic-pathological determinations:
a) sharp inflammation; b) oedema; c) non-specific chronic inflammatory infiltrate; d) granulomatous inflammatory
infiltrate to foreign bodies; e) fibrosis.
RESULTS. The results obtained indicate a greater anastomoses' tensile strength for group 2 and 3. The anatomic-pathological
values show a better response to anastomoses with adhesives than with conventional sutures.
CONCLUSIONS. All these experimental results lead us to conclude that the cyanocrilates used to carry out sutureless anastomoses
may be an alternative to the handmade conventional anastomoses. Moreover they are easy to be implemented.
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