Surgical treatment for hepatic metastases from colorectal carcinoma

Objective To explore the indications and effect of surgi ca l resection for hepatic matastases from colorectal adenocarcinoma and to discuss the implications of clinicopathologic features on the prognosis. Methods A retr ospective study of 61 patients undergoing hepatectomy for metastatic tumors from colorectal adenocarcinoma from January 1991 to December 2000 in our hospital wa s performed retrospectively. Results The 1-,3- and 5-year survival rates a fter hepatic resection were 72.13% ,58.10% and 26.01% respectively. Complic ations occurd in 8 cases. Tumor pesudomembrance was found in 20 cases. Dukes sta ge,pathologic type,the number of hepatic metastases and tumor pesudomembrance we re all significant factors for prognosis after surgery(P 0.05). The 3-year su rvival rate of the patients with postoperative comprehensive treatment was highe r than that with non-postoperative treatment(P 0.05). The size of hepatic met astases and the resecting time didn t affect the prognosis(P 0.05). Conclusio n The hepatic metastases from colorectal cancer should be treated by a surgical approach. The earlier stage of clinical pathology,higher differentiation extent, metastases less than 3,the formation of pesudomembrance of the metastatic tumor and the postoperative comprehensive treatment predict a better survival.