Recommended vitamin D levels in the general population

Abstract Objective To provide recommendations based on evidence on the management of vitamin D deficiency in the general population. Participants Members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology. Methods Recommendations were formulated using the GRADE system (Grading of Recommendations, Assessment, Development, and Evaluation) to describe both the strength of recommendations and the quality of evidence. A systematic search was made in MEDLINE (Pubmed) using the term Vitamin D and the name of each issue. Papers in English and Spanish with publication date before 17 March 2016 were included. Recommendations were jointly discussed by the Working Group. Conclusions This document summarizes the data about vitamin D deficiency in terms of prevalence, etiology, screening indications, adequate levels and effects of supplementation on bone and non-skeletal health outcomes.