Biological optimization of the dose in elderly patients.

: The incidence of tumors in elderly people is constantly growing. Because of the advanced-age associated physiological alterations, in the treatment of the elderly the evaluation of correlated morbidities cannot be overlooked. Most likely, the presently available technologies pave a new way to radiotheray in the possibility of personalized treatments and biological optimization of the dose (e.g. with special techniques as IMRT, stereotaxy) to provide treatment plans suitable for the patient clinicopathological conditions while keeping in mind the evaluation of quality life.