On the formation of the 1-aza-[3.1.1]-bicycloheptane ring system

J. A. Christensen,Mogens Engelstoft,K. Schaumburg,Henning Schou,F. Wätjen

On the formation of the 1-aza-[3.1.1]-bicycloheptane ring system

1983

J. A. Christensen
Mogens Engelstoft
K. Schaumburg
Henning Schou
F. Wätjen

Abstract The previously unpublished bicyclic system 1-aza-[3.1.1]-bicycloheptane has been shown to exist as an unexpected intermediate in the synthesis of Femoxetine, a CNS active drug. 1

Keywords:

SN2 reaction
Femoxetine
Steric effects
Bicyclic molecule
Organic chemistry
Stereochemistry
Chemistry

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