SIK1 localizes with nephrin in glomerular podocytes and its polymorphism predicts kidney injury.

SIK1 localizes with nephrin in glomerular podocytes and its polymorphism predicts kidney injury M. Ferrandi1,2, I. Molinari1,2, V. Matafora3, G. Zerbini4, F. Trevisani5, M.P. Rastaldi6, M. Simonini5, L. Giardino6, P. Ferrari1,7, and P. Manunta2,8 Prassis Sigma-tau Research Institute, Via Forlanini, 3, Settimo Milanese, Milan, Italy, Division of Genetics and Cell Biology, Genomics of Renal Diseases and Hypertension Unit, Division of Genetics and Cell Biology, Biomolecular Mass Spectrometry Unit, Division of Metabolic and Cardiovascular Sciences, Complications of Diabetes, and Department of Internal and Specialistic Medicine, San Raffaele Scientific Institute, Milan, Italy, Renal Research Laboratory, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico & Fondazione D’Amico per la Ricerca Sulle Malattie Renali, Milan, Italy, CVie Therapeutics, Hong Kong, China, and Universita Vita-Salute San Raffaele, San Raffaele Scientific Institute, Milan, Italy