Normative Data Assessment of Vessel Density and Foveal Avascular Zone Metrics Using AngioScan Software

AbstractPurpose:To establish a normative database for macular and peripapillary vessel densities (VD) and foveal avascular zone (FAZ) metrics in healthy subjects with the new version of AngioScan software of RS-3000 Advance (Nidek Co, Ltd) optical coherence tomography angiography (OCT-A) device.Methods:The study design was prospective and cross-sectional. VDs of the SCP, deep capillary plexus (DCP), retinal peripapillary capillary plexus (RPCP) and FAZ area, perimeter and circularity index (CI) along with the structural OCT measurements were scanned by using the Nidek’s RS-3000 Advance OCT-A device in healthy subjects. The new version of the AngioScan software was used for analytics. The relations between the OCT-A parameters with age, gender and OCT parameters were analyzed.Results:A total of 128 right eyes of 128 subjects (50% female) were included in this study. We divided subjects into 3 groups in accordance with age; 19-39 years to Group 1, 40-59 years to Group 2, >60 y. to Group 3. The mean SCP and ...