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Antibacterial gel of eye drops

2001 
An object of the present invention is to improve the utilization efficiency of the drug, and, levofloxacin there is little risk resulting side effects, ofloxacin, or, moxifloxacin or an antibacterial gel and a pharmaceutically active ingredient acceptable salt ophthalmic it is to provide an agent. The present invention is a antimicrobial gelling ophthalmic solution containing an antimicrobial agent and gellan gum, wherein the antimicrobial agent is levofloxacin, ofloxacin, and is selected from the group consisting of moxifloxacin, or a pharmaceutically acceptable salt thereof at least one antimicrobial agent concentration in the eye in the case of instillation of the antibacterial gelling ophthalmic agent, antibacterial agent concentration in the eye in the case of instillation of eye drops having a composition excluding the gellan gum from the antibacterial gelling ophthalmic solution respect, in the conjunctiva is 3 times or more, and, in the aqueous humor is an antibacterial gelling ophthalmic solution is less than 3 times.
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