Additional polymorphisms of the PRNP gene significantly decrease the susceptibility to scrapie of ARQ/ARQ sheep

Caterina Maestrale,Antonello Carta,Sonia Attene,Stefania Sechi,Adriana Galistu,Cinzia Santucciu,Giovanna Maria Cancedda,Mariangela Saba,Cristiana Patta,Ennio Bandino,Franca Demontis,Patrizia Uras,Ciriaco Ligios

Additional polymorphisms of the PRNP gene significantly decrease the susceptibility to scrapie of ARQ/ARQ sheep

2007

Caterina Maestrale
Antonello Carta
Sonia Attene
Stefania Sechi
Adriana Galistu
Cinzia Santucciu
Giovanna Maria Cancedda
Mariangela Saba
Cristiana Patta
Ennio Bandino
Franca Demontis
Patrizia Uras
Ciriaco Ligios

The aim of this work was to investigate the risk of scrapie of the ARQ/ARQ genotype carrying at least one point mutation at codons 112, 137, 141, 142, 154 and 176 in comparison with the ARQ/ARQ without any point mutations.

Keywords:

Scrapie
PRNP
Genotype
Genetics
Gene
Point mutation
Biology
Virology
prnp gene

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