Ferrous fumarate folic acid dispersible tablet and preparation method thereof

2009 
The invention discloses a ferrous fumarate folic acid dispersible tablet and a preparation method thereof; the dispersible tablet is composed of 35-45 percent of composite of ferrous fumarate and folic acid and an acceptable carrier in pharmacy by mass percent; the mass ratio of ferric ions and folic acid in the composite of ferrous fumarate and folic acid is 150:1: the acceptable carrier in pharmacy comprises 30-60 percent of fillers, 2-10 percent of binding agents, 3-15 percent of disintegrants and 0.5-5 percent of lubricants by mass percent; the dispersible tablet is prepared by a wet granulation tabletting method and is rapidly disintegrated and evenly dispersed when meeting water, the effect is rapid, the bioavailability is high, and adverse reaction caused by overhigh local drug concentration of gastrointestinal tract can be alleviated or avoided, and the carrying and medicine taking are convenient; the preparation process is simple, the cost is low, the preparation is stable, safe and effective, thereby being suitable for industrial production.
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