Acute kidney allograft injury following vitamin C administration for septic shock

Sepsis is a highly prevalent disease in intensive care units and is associated with significant morbidity and mortality. More than 20% of all septic patients develop acute kidney injury, and the deteriorating kidney function is liable to be classified by most clinicians as septic kidney injury. This presumption is, however, only very occasionally confirmed by kidney biopsy, mainly because of the low rate of treatment-changing results as well as to the increased rate of adverse events. However, acute kidney injury in this setting can be caused by other, unexpected factors that we will highlight by way of the following case example.