A New, Convenient Synthesis of 1,6‐Diaryl‐2‐thioxoperhydro‐4‐pyrimidinones: Reaction of 3‐Phenyl‐2‐propenoyl Isothiocyanate With Aromatic and Heteroaromatic Amines

The substitued thioureas 3a–h, prepared form 3-phenyl-2-propenoyl isothiocyanate (1) and aromatic or heteroaromatic amines 2a–h, cyclize in the presence of sodium ethoxide to give the perhydropyrimidine derivatives 5a–c.