1H and13C NMR spectra of 3-substituted 4-quinolones

A series of 14 3-substituted 4-oxoquinolones with or without a substituent (methyl, ethyl) in position 1 were prepared. Literature and measured data were used to study the influence of the substituent on the shifts of carbon atoms of these compounds, which are model compounds for antibacterial drugs of the nalidixic acid type. ©1998 John Wiley & Sons, Ltd.