Abstract 13940: Using an Angiotensin Converting Enzyme Inhibitor to Treat Cardiovascular and Cognitive Decline in a Rat Model of Vascular Dementia

Jennifer Shearon,Rachel C. Fenner,Yulia Grigorova,Ross A. McDevitt,Samuel Ajamu,Valentina Zernetkina,Wen Wei,Jeffrey C. Long,Peter R. Rapp,Edward G. Lakatta,Olga V. Fedorova

Abstract 13940: Using an Angiotensin Converting Enzyme Inhibitor to Treat Cardiovascular and Cognitive Decline in a Rat Model of Vascular Dementia

2020

Jennifer Shearon
Rachel C. Fenner
Yulia Grigorova
Ross A. McDevitt
Samuel Ajamu
Valentina Zernetkina
Wen Wei
Jeffrey C. Long
Peter R. Rapp
Edward G. Lakatta
Olga V. Fedorova

Background: Aged Dahl salt sensitive rats (DSS) rats represent a model of vascular dementia, i.e., they develop central arterial stiffness (CAS), hypertension, and cognitive decline. DSS rats have ...

Keywords:

rat model
Endocrinology
Angiotensin-converting enzyme
Fibrosis
Internal medicine
hypertension experimental
Medicine
Dahl Salt-Sensitive Rats
cognitive decline
Arterial stiffness
Vascular dementia

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