Cavernous Sinus Thrombosis

A 34-year-old woman with a 3-year history of systemic lupus erythematosus was admitted to the hospital with sore throat and headache that had lasted for 3 weeks. She had been receiving cyclophosphamide for lupus nephritis for the previous 2 years. On the eighth hospital day, she reported severe headache and bilateral pain and bruising of the eyes. A day later, proptosis developed, with severe chemosis and eyelid edema, and her pupils were bilaterally nonreactive to light on examination. A preliminary diagnosis of extensive intracranial venous thrombosis was confirmed on magnetic resonance imaging. Axial T2-weighted imaging at the level . . .