Peculiarity of changes of peripheral blood hematological indices in rats under N-stearoilethanolamine administration conditioned by combined effects of ionizing radiation and stress.

UNLABELLED: Objective - to investigate the peculiarities of peripheral blood indices changes in rats under the N-stearoiletanolamine treatment before and after combined effects of ionizing radiation and stress. METHODS: hematological, statistical. RESULTS: Per oral administration of NSE (10,0 mg / kg) before and after the combined effects of single whole-body irradiation (6.0 Gy) and emotionally-algesic stress (foot-shock) leads to reduction in the number of circulating peripheral blood cells, increasing signs of damage of the hematopoietic system with accelerated exhaustion processes. Conclusions. NSE administration (10,0 mg / kg) in rats under the combined influence of ionizing radiation (6 Gy) and emotionally-algesic stress slows down the course of regenerative processes and accelerates the depletion of the hematopoietic system, proving for its radiosensitizing effects.