Effect of thyrocalcitonin on periodic motor activity of the gastro-intestinal tract

Experiments on dogs with fistulas of the stomach and various parts of the small intestine, in which periodic motor activity was recorded, showed that intravenous injection of highly purified bovine thyrocalcitonin (TCT) in doses of 2–10 units/kg (much higher than the doses used clinically for the treatment of patients with bone pathology), does not cause changes in the indices of periodic motor activity of the stomach or the various parts of the small intestine despite a definite decrease (by 10–20%) in the serum calcium level.