Enantioselective Bromolactonization of Deactivated Olefinic Acids­: Studies Toward the Synthesis of Brominated Isochroman-1,4-diones

Enantioselective bromolactonization using an amino-carbamate­ catalyst to generate brominated isochroman-1,4-diones is described. Excellent yields and moderate enantioselectivities were achieved.