Variation in SARS-CoV-2 Infection Risk and Socioeconomic Disadvantage Among a Mayan-Latinx Population in Oakland, California.

US Latinx populations are disproportionally affected by the SARS-CoV-2 pandemic, with higher rates of infection and associated morbidity and mortality.1 Although often treated as homogeneous, members of Latinx communities vary by national origin, immigration status, and language.2 Oakland, California, is home to many Latinx individuals and an estimated 10 000 Mayan individuals, many of whom speak Indigenous languages.3 Early in the pandemic, community-based organizations (CBOs) in Oakland, California, observed a high frequency of infections among Latinx individuals in general and even higher frequency among Mayan individuals.4 Local CBOs, the University of California, San Francisco (UCSF), and public health authorities formed a collaborative to offer diagnostic testing in Fruitvale, a diverse neighborhood that has among the highest cumulative infection rates in Alameda County.5 Using data from the resulting SARS-CoV-2 testing event, we examined variation in infection risk and socioeconomic disadvantage within the Fruitvale community.