A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma

Christian C. Abnet,Neal D. Freedman,Nan Hu,Zhaoming Wang,Kai Yu,Xiao-Ou Shu,Jian-Min Yuan,Wei Zheng,Sanford M. Dawsey,Linda M. Dong,Maxwell P. Lee,Ti Ding,You-Lin Qiao,Yu-Tang Gao,Woon-Puay Koh,Yong-Bing Xiang,Ze Zhong Tang,Jin Hu Fan,Chaoyu Wang,William Wheeler,Mitchell H. Gail,Meredith Yeager,Jeff Yuenger,Amy Hutchinson,Kevin B. Jacobs,Carol Giffen,Laurie Burdett,Joseph F. Fraumeni,Margaret A. Tucker,Wong Ho Chow,Alisa M. Goldstein,Stephen J. Chanock,Philip R. Taylor

A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma

2010

Christian Abnet and colleagues report genome-wide association studies for gastric adenocarcinoma and esophageal squamous cell carcinoma in a Chinese population. They identified a new shared risk locus in the PLCE1 gene at 10q23.

Keywords:

Carcinoma
Stomach cancer
Genetics
PLCE1
Locus (genetics)
Cancer
Esophageal disease
Population
Biology
Adenocarcinoma
Gene mapping
Allele frequency

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