A case of tuberculous encephalopathy with multiple intracranial tuberculomas

: A case of 56-year-old man with tuberculous encephalopathy following pulmonary tuberculosis was reported. Computed tomography (CT) revealed low density virtually confined to the white matter of the cerebral hemisphere. Contrast enhanced CT demonstrated intracranial multiple spotted lesions, all of which were homogeneously enhanced, supporting multiple intracranial tuberculomas. Magnetic resonance miss spelling imaging (MRI) suggested brain edema and demyelination of the white matter. Clinically this case was characterised by evidence of diffuse cerebral involvement in the form of convulsions, abnormal behavior and consciousness impairment without significant signs of meningitis. Antituberculous chemotherapy improved both clinical symptoms and intracranial lesions on CT and MRI. These findings strongly suggested the diagnosis of tuberculous encephalopathy with multiple tuberculomas. No adult case of tuberculous encephalopathy with multiple intracranial tuberculomas has been previously reported.