Effects of the use of fibrin glue around the colonic anastomosis of the rat.
2003
This study was aimed at examining whether the addition of
fibrin glue to a sutured colonic anastomosis improves its
healing or not. We studied the effect of adding fibrin glue on a sutured
colonic anastomosis. Thirty-six Wistar rats were randomized into
two groups of 18 rats each. A sutured anastomosis was performed
in all rats. Fibrin glue was applied around the anastomosis of
the rats of group B. Rats were sacrificed on the eighth
postoperative day. The rate of anastomotic leakage was found not to be
significantly different between the two groups. The mean
bursting pressure of the colonic anastomoses was significantly
higher in group B (fibrin-treated) than in group A. Fibrin glue application around a sutured anastomosis
provides a safer anastomosis which is stronger than the sutured
one.
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