Polymethylmethacrylate pulmonary embolism as a complication of percutaneous vertebroplasty in cancer patients.

Abstract Percutaneous vertebroplasty is frequently used in the treatment of vertebral body fractures due to osteoporosis, vertebral body metastasis, or myeloma. Acrylic cement of polymethylmethacrylate injected into the vertebral body can leak into the paravertebral venous system and reach the pulmonary artery via the azygos vein leading to a cement pulmonary embolism. We are presenting a case of a 78 year old woman who was found to have polymethylmethacrylate pulmonary embolism as a result of vertebroplasty used for vertebral collapse from metastatic breast cancer. The appearance of new intrapulmonary artery tubular opaque density on CXR performed post procedure is highly suggestive of the diagnosis. In this case, we are exploring the importance of clinical and radiographic correlations, as well as evaluation of the hemodynamic and perfusion effect of the cement pulmonary embolism as essential steps in the management of this condition.