Contribution of the Gastrointestinal Tract to Lorazepam Conjugation and Clonazepam Nitroreduction

Hermann R. Ochs,David J. Greenblatt,Wolfgang Eichelkraut,Barbara W. LeDuc,James F. Powers,Norbert Hahn

Contribution of the Gastrointestinal Tract to Lorazepam Conjugation and Clonazepam Nitroreduction

1991

Hermann R. Ochs
David J. Greenblatt
Wolfgang Eichelkraut
Barbara W. LeDuc
James F. Powers
Norbert Hahn

Domestic pigs received single intravenous and oral doses of lorazepam or clonazepam (1 mg/kg), benzodiazepine derivatives biotransformed by glucuronide conjugation and nitroreduction, respectively. Bl

Keywords:

Absorption (pharmacology)
Gastrointestinal tract
Endocrinology
Internal medicine
Benzodiazepine
Lorazepam
Glucuronidation
Bioavailability
Glucuronide
Chemistry
Anesthesia
Clonazepam
Pharmacology
Oral administration
Pharmacokinetics

Correction
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